35 articles - From Friday Oct 03 2025 to Friday Oct 10 2025
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Am J Clin Nutr |
|---|
| Assessment of arsenic, cadmium, lead, mercury, and per- and polyfluoroalkyl substances concentrations in human milk and infant formula in the United States: a systematic review.
In published, peer-reviewed United States studies, PFOA and PFOS were detected in HM; PFAS were largely undetected in IF. There was a paucity of contemporary evidence for arsenic, cadmium, lead, and mercury in HM or IF in the United States, but we identified evidence from other countries that could help inform these knowledge gaps. Public health agencies recommend feeding infants HM given the benefits outweigh potential risks of contaminant exposure. |
| J Crohns Colitis |
| Glucagon-Like Peptide 1 Receptor Agonists (GLP1-RA) and the Clinical Outcomes of Inflammatory Bowel Disease (IBD): A Systematic Review and Meta-analysis.
Interpretation Patients with IBD and obesity using GLP1-RAs were able to achieve significant weight loss and had lower risks of surgery and hospitalizations. Our findings require confirmation in prospective trials of GLP1-RAs in IBD. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
| Effect of saffron extract supplementation on mood in healthy adults with subclinical symptoms of depression: A randomized, double-blind placebo-controlled study.
Saffron extract supplementation did not affect subclinical depressive symptoms, either measured as a composite score or individual symptom categories. A potential effect on improved mental health outcomes cannot be excluded but requires further replication in future well-powered trials. Saffromfood study, clinicaltrial.gov NCT05690126. |
| Erythromycin plus metoclopramide combination therapy compared with erythromycin or metoclopramide monotherapy for postpyloric spiral nasoenteric tube placement: a multicenter, open-label, randomized controlled superiority trial.
The combination therapy of erythromycin and metoclopramide was not superior to erythromycin or metoclopramide monotherapy in facilitating postpyloric placement of spiral NETs in critically ill patients. However, the combination therapy was associated with a higher incidence of drug side effects compared with the metoclopramide monotherapy. The trial was registered with (trial ID ChiCTR1900022508). |
| Lanthanum carbonate lowers serum phosphorus without altering body phosphorus burden in maintenance peritoneal dialysis patients: a randomized crossover trial.
Methods Seven adult patients undergoing maintenance peritoneal dialysis underwent full metabolic balance studies for phosphorus in a research ward while they ate a constant phosphorus diet. Patients were studied during a baseline period without phosphate binders and while they received, in random order, 3 doses of lanthanum carbonate (La treatment lowered serum phosphorus concentration but did not change body phosphorus content. |
| Mediterranean diet, metabolic signature, genetic predisposition, and risk of rheumatoid arthritis: a large-scale population-based prospective cohort study.
We identified a robust metabolic signature reflecting the metabolic response to the MED diet. This signature was inversely associated with RA risk and partially mitigated the genetic susceptibility to RA. These findings highlight the potential of metabolic signature for enhancing dietary assessment and guiding personalized nutritional intervention. |
| Optimizing management of uncomplicated acute malnutrition in children in rural Niger: a 3-arm individually randomized, controlled, noninferiority trial.
Only the ComPAS protocol demonstrated noninferiority to standard treatment in ITT and PP analyses for children with MUAC <125 mm or edema. The OptiMA protocol's lower performance is unclear, but it suggests that reduced RUTF dosage had limited influence on overall child growth, as ComPAS used less RUTF than OptiMA. For the most malnourished children with MUAC <115 mm or edema, the standard protocol showed a higher recovery proportion, primarily due to better attendance rather than differences in mortality or growth at 6 mo. Further studies are needed to better understand the acceptability and population-level impact of simplified protocols in multiple settings. |
| Sugar restriction in the first 1000 days after conception, and long-term respiratory health: a quasi-experiment study.
Restricting sugar intake during the first 1,000 d after conception was associated with reduced risk and delayed onset of asthma and COPD, and improved lung function in adulthood. These findings support the utility of current dietary guidelines to promote lifelong respiratory health. |
| Sustainable diets reduce diet-related greenhouse gas emissions and improve diet quality: results from the MyPlanetDiet randomized controlled trial.
Personalized sustainable dietary advice led to healthier diets and lower diet-related GHGE with no short-term negative health effects. This trial was registered with clinicaltrials.gov as NCT05253547 ( |
| The carbon isotope ratio of alanine is a biomarker of added sugar and sugar-sweetened beverage intakes: a pooled analysis of four studies.
The Ala CIR is a robust biomarker of AS/SSB intake. Potential associations with APR can be adjusted for using a simultaneously-measured biomarker. Clinical trial registry number (DBD study) clinicaltrials.gov/NCT01237093; (NPAAS) clinicaltrials.gov/NCT00000611. |
| Trends in vitamin D status in the United States, 2007-2023: a cross-sectional analysis of data from the National Health and Nutrition Examination Survey.
The proportion of the population with inadequate vitamin D concentrations continues to decline, and the proportion of the population with high vitamin D concentrations continues to rise. These trends are especially apparent among individuals reporting use of vitamin D-containing supplements. |
| Ultraprocessed foods consumption, inflammatory index levels, and risk of suicide attempt: findings from a prospective cohort study.
Higher UPF consumption is associated with an increased risk of SA, partially mediated by inflammatory index levels. Replacing UPF with UNPF significantly reduces SA incidence, highlighting potential benefits of transitioning to a diet with higher UNPF consumption. |
| Inflamm Bowel Dis |
| Comparison of Different Sites of Microbiota Shows Increased Pseudomonas Species in the Gut Mucosa in Inflammatory Bowel Disease.
The opportunistic pathogenic bacterium Pseudomonas species is more prevalent in the gut mucosa of patients with IBD. This indicates a disruption of the gut barrier with increasing mucosal colonization or invasion of the bacteria. The finding is independent of clinical metadata and confounders and occurs in new-onset IBD but not in non-IBD intestinal inflammation, which suggests disease specificity. |
| Health-Related Physical Fitness in Patients With Inflammatory Bowel Disease vs Healthy Control Subjects.
Patients with IBD have higher body fat and reduced cardiorespiratory fitness and muscular strength compared with healthy control subjects. Especially, patients with a higher age, female sex, higher body mass index, fatigue, arthritis, or multiple biologicals used are at risk for such impairments and may benefit from physical exercise interventions. |
| J Crohns Colitis |
| Comprehensive proteomic profile in newly diagnosed patients with inflammatory bowel disease: identification of potential biomarkers.
This comprehensive proteomic study has identified a set of proteins differentially expressed in IBD, which may contribute to a better understanding of its mechanisms and hold promise as candidate biomarkers. Although these findings are preliminary, they warrant further investigation to evaluate their diagnostic and therapeutic relevance. |
| Disease duration impacts intestinal gene expression profiles in crohn's disease but not in ulcerative colitis.
Disease duration influences intestinal gene expression in CD but significantly less in UC. The identified pathways and genes may inform development of differing biomarkers and treatment strategies in shorter versus longer standing CD. |
| Liver Transpl |
| Evolving trends and comparative outcomes of bridging transarterial locoregional therapy in liver transplant candidates with hepatocellular carcinoma.
The use of transarterial radioembolization as bridging therapy in HCC liver transplant candidates has surged, and is influenced by socioeconomic factors, comorbidities, and tumor burden. Transarterial radioembolization effectiveness has been demonstrated by its advantages in waitlist retention and tumor necrosis. Further studies are warranted to evaluate its impact on post-liver transplant recurrence and to validate the cost-effectiveness among transarterial therapies. |
| Gender disparity in access to early liver transplant among patients with alcohol associated liver disease and limited sobriety is mediated by psychosocial factors.
Notable gender disparities in access to LT exist among patients with ALD evaluated with <6 months of sobriety. Lower waitlisting in women is mediated by higher rates of psychiatric conditions and lower rates of employment, though gender-specific alcohol-related bias may also contribute. |
| Pancreas |
| "Pancreatic Calcification and Pathologic Fibrosis Score: Correlation with Islet Yield and Insulin Independence after Total Pancreatectomy with Islet Autotransplantation TPIAT".
Increasing severity of calcification burden in the pancreatic body/tail was associated with around 1500 IEQ/kg reduction in islet yield following TPIAT for chronic pancreatitis. The presence of pancreatic head calcifications may be associated with more favorable islet yield. |
| Single Versus Dual Drainage of Walled-Off Pancreatic Necrosis.
In patients receiving initial EUS drainage, the rate of step-up to DMD was 33.9%, highlighting that 2/3 of those with WOPN can be successfully managed by endoscopic means alone. Large size and pericolic extension were identified as predictors for need for step-up, and such features may be useful in identifying patients who may benefit from early dual approach. |
| Pancreatology |
| Clinical outcomes and risk factors of invasive candidiasis in patients with infected pancreatic necrosis.
IPN Patients complicated by invasive candidiasis exhibited a relatively low overall response to antifungal therapy. Breakthrough fungal infection was identified as an independent risk factor for early therapy failure, while septic shock and isolated pancreatic fungal infection were significantly associated with therapy failure at the end of intravenous therapy. Multiple organ dysfunction syndrome was an independent predictor of 28-day mortality. |
| Efficacy of diagnosing intraductal papillary mucinous neoplasm with mural nodules by contrast-enhanced endoscopic ultrasound using time-intensity curve analysis with a new support program: A multicenter retrospective study (with video).
The contrast ratio calculated using TIC analysis with the support program is potentially useful for differentiating between IPMNs with LGD and those with HGD/IC. |
| Preoperative aerobic fitness is a predictor of postoperative outcomes in patients undergoing pancreatoduodenectomy.
Low preoperative aerobic fitness is prevalent in patients undergoing pancreatoduodenectomy and a predictor of impaired postoperative outcomes. Aerobic fitness should therefore be included in the preoperative work-up and optimized accordingly in unfit patients scheduled to undergo pancreatoduodenectomy. |
| Prognostic impact of serum triglycerides in acute pancreatitis: Evidence from multi-center cohort study using a common data model.
HTG is associated with a higher risk of developing severe AP. Younger patients (<60 years) with HTG may be vulnerable to a more severe disease course. |
| Total pancreatectomy with islet auto-transplantation in pediatric patients results in significantly decreased opioid use, improved long-term pain and quality of life outcomes.
Utilizing a standardized multidisciplinary approach to TPIAT in pediatric patients with pancreatitis showed significant decreases in opioid use and abdominal pain, regardless of severity of disease, pain, or opioid use pre-TPIAT. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Am J Clin Nutr |
|---|
| Fewer bites of beef to make an impact: even small changes toward a more sustainable diet and lifestyle can meet personal and public health goals while addressing planetary health. |
| Protecting infants from environmental contaminants in milk and formula: addressing assessment gaps and advancing next steps. |
| Target the dose, mind the context: priorities for pediatric acute malnutrition treatment in an era of declining global food assistance. |
| Time to take diet and mental health research seriously. |
| Pancreatology |
| Cracking the code to early detection of pancreatic cancer using AI. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Liver Transpl |
|---|
| Preliminary experience with RAPID auxiliary liver transplantation using a partial graft retrieved after circulatory death and split under hypothermic oxygenated machine perfusion. |
| Pancreas |
| The Silent Surge: Why Pancreatic Cancer Demands an Early Detection Revolution. |
| Pancreatology |
| A model to predict participant retention in longitudinal acute pancreatitis studies. |
| Risk of acute and chronic pancreatitis in patients with psoriasis: A Danish nationwide cohort study. |